Editor's note: This is the first part of a two-part series on this topic.
For many years there have been theories that autoimmune diseases, such as systemic lupus erythematosis, rheumatoid arthritis (RA is not the "wear and tear or osteoarthritis, but OA can also respond), sarcoidosis, uveitis, Crohn's disease, ulcerative colitis and other similar syndromes such as chronic fatigue, fibromyalgia rheumatic, immune deficiency, multiple chemical sensitivity, multiple sclerosis, amyotrophic lateral sclerosis (Lou Gherig's disease), Parkinson's, restless leg's, myasthenia gravis, interstitial cystitis, kidney stones, psoriasis, cardiac arrhythmias, non-insulin dependent diabetes, irritable bowel syndrome, and similar disorders may be linked to an infection that is hard to diagnosis and harder to cure.
We've learned that diseases, such as coronary artery disease, and even stomach ulcers have been linked to unusual organisms as well. These have been equally difficult and slow to understand, diagnose and effectively treat.
Over the years many physicians have prescribed a variety of antibiotics hoping to help those suffering from these and other similar disease. We've had little success and our patients' precious little relief.
Enter Trevor Marshall, who obtained his doctorate from the University of Western Australia. He's since moved to Southern California and has developed a protocol that seems to effectively find and target cell-wall deficient bacteria, classically known as l-forms, that are ingested by the white blood cells of our body's immune system.
Usually, germs are killed once ingested this way, but these bacteria have adapted to be able to survive and cause further damage after they've been engulfed. The diseases linked with these organisms cause a great deal of suffering to our patients.
Many physicians feel helpless and frustrated trying to treat patients with myriad vague complaints without classic medical findings on exam and/or lab and imaging.
The process is more than a little bit complicated, as is the cure for it.
Dr. Marshall has found that there is an immune system component, the Th-1 system that actually uses the cell's vitamin D receptors to help regulate the inflammatory process.
Basically, these bacteria are able to fool the immune system using this receptor. They keep the immune system very active, churning away, using up a lot of energy, while not actually getting rid of the organism.
It's important to understand a little bit about vitamin D in order to see how this works.
Vitamin D comes in a preliminary form; 25-hydroxy vitamin D, which is then activated to the more active 1,25 di-hydroxy form.
Typically, folks with this disorder have low 25 hydroxy and very high 1,25 di-hydroxy forms of vitamin D. We can draw blood levels, which are immediately frozen, and look for a ratio of greater than 1.6 dihydroxy/25 hydroxy to diagnose that this syndrome is likely causing our patient's problems.
The CWD bacteria are actually causing this over-abundance of di-hydroxy vitamin D. This excess of substances stimulates large numbers of macrophages to become active and release cell-regulating chemicals that cause increased pain, inflammation, fatigue and other symptoms over time. They also stimulate formation of angiotensin II production, which gives us a foothold in how to treat the disorder.
There is a class of blood pressure medicines called angiotensin receptor blockers that work to block that part of this sequence.
Of this class of drugs, olmesartan (Benicar is the trade name and will be used for convenience in this article) works the best.
Unfortunately, there is a toxic reaction as these CWD's die off. They release toxins that cause a Jarisch-Herxheimer (Herx for short) reaction that causes a variety of symptoms, usually the symptoms the patient suffered initially. These symptoms can present in a huge number of ways. If they involve the heart and lungs, they can be potentially life threatening and should not be taken lightly or without the assistance of a physician comfortable in dealing with serious illnesses and symptoms.
For readers intrigued by the concept of using antibiotics to CURE and not settle for controlling symptoms of the many forms of Th-1 inflammation, further information is available at www.marshallprotocol.com
It's strongly encouraged to patients that they register at the site and receive the free expert advice from the professionals at this site to those suffering from these diseases by posting questions after registering on the site. There is no charge for this service.
R.J. Oenbrink of Tequesta Family Practice is a board certified doctor of osteopathy. His offices are located at 395 Tequesta Drive, Suite B. Send your questions to: firstname.lastname@example.org. He is available to speak to groups on this or a variety of other topics. Please call his office, if interested, at (561) 746-4333.